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News, Publication

Investigating combination HIV prevention: isolated interventions or complex system

14 Dec, 2015
By: Graham Brown, Daniel Reeders, Gary W Dowsett, Jeanne Ellard, Marina Carman, Natalie Hendry, Jack Wallace

Treatment as prevention has mobilized new opportunities in preventing HIV transmission and has led to bold new UNAIDS targets in testing, treatment coverage and transmission reduction. These will require not only an increase in investment but also a deeper understanding of the dynamics of combining behavioural, biomedical and structural HIV prevention interventions. High-income countries are making substantial investments in combination HIV prevention, but is this investment leading to a deeper understanding of how to combine interventions? The combining of interventions involves complexity, with many strategies interacting with non-linear and multiplying rather than additive effects.

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